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Jae Choi

M.D., M.S.

Focus Areas

  • Arteriovenous Malformations (AVM)

Dr. Jae Choi is a brain aneurysm neurologist specializing in vascular diseases. His clinical and academic focus has been in the diagnosis and management of acute and chronic cerebrovascular conditions that often greatly impact the quality of life of patients. These conditions include acute ischemic stroke, atherosclerotic disease of the carotid artery, arteriovenous malformations of the brain, and brain aneurysms, among others. Dr. Choi has been particularly interested in studying the triggers for the occurrence and progression of vascular diseases and their symptoms, so called risk factors, and the clinical management thereof. The overall goal of this management is to protect the brain from damages (neuroprotection) that includes not only medical and surgical treatment, but also information, patient education, and behavioral modifications. In order to improve our understanding and the treatment of these complex cerebrovascular conditions, it is essential to continuously engage in a collaborative process with other disciplines and the patient, who is without doubt, the most important stake holder.

As the Medical Director of the Unruptured Brain Aneurysm Center, Dr. Choi will lead this program together with Dr. Pile-Spellman to provide specialized care for patients who live with unruptured brain aneurysms. With more than 800 patients with unruptured brain aneurysms followed over an average duration of 5 years we have a clear and unique opportunity. We believe that the result of this collaborative endeavor will lead to better management and ultimately, will improve the lives of many patients.

Dr. Choi graduated in medicine from the Martin-Luther University in Halle, Germany and obtained a doctoral degree from the Charité in Berlin, Germany. Following his neurology residency at the Academic Hospital Bergmannstrost in Halle, Germany, a Level I trauma center and tertiary stroke center, he completed two fellowships at the Columbia University Medical Center in New York, at the Neurological Institute, Stroke Center and at the Department of Radiology, the Division of Academic Interventional Neuroradiology and Interventional MRI. Dr. Choi was an Assistant Professor and Co-Director of the Doppler Laboratory of the Department of Neurology, Stroke Center at the Columbia University Medical Center and has been principal investigator and co-principal of grant programs funded by the government, foundations, and academic institutes. He is actively involved in the development of medical technology, is a professional member of US and European medical societies, and reviewer for medical journals. Dr. Choi is an Adjunct Assistant Professor of the Department of Neurology at the State University of New York in Brooklyn, NY.


Choi JH, Mohr JP. Brain arteriovenous malformations in adults. Lancet Neurology 2005; 4: 299–308.
Choi JH, Bateman BT, Mangla S, Marshall RS, Prabhakaran S, Chong J, Mohr JP, Mast H, Pile-Spellman J. Endovascular recanalization therapy in acute ischemic stroke. Stroke 2006; 37: 419-24.

Choi JH, Mohr JP, Sciacca RR, Hartmann A, Khaw AV, Mast H, Sacco RL, Stapf C. Clinical outcome after first and recurrent hemorrhage in patients with untreated brain arteriovenous malformation. Stroke 2006; 37: 1243-47.

Konstas AA, Choi JH, Pile-Spellman J. Neuroprotection for ischemic stroke using hypothermia. Neurocritical Care 2006; 4: 168-178.

Stapf C, Mast H, Sciacca RR, Choi JH, Hartmann A, Khaw AV, Mohr JP. Predictors of hemorrhage in patients with untreated brain arteriovenous malformation. Neurology 2006; 66: 1350-55.

Choi JH, Jakob M, Stapf C, Marshall RS, Hartmann A, Mast H. Multimodal Early Rehabilitation and Predictors of Outcome in Survivors of Severe Traumatic Brain Injury. J Trauma 2008; 65:1028-35.

Prabhakaran S, Chen M, Choi JH, Mangla S, Lavine SD, Pile-Spellman J, Meyers PM, Chong JY. Major neurologic improvement following endovascular recanalization therapy for acute ischemic stroke. Cerebrovasc Diseases 2008; 25: 401-407.

Mast H, Hofmeister C, Choi J, Stapf C, Sabel BA. A randomized trial of vision restoration therapy. AktNeurol 2008; doi: 10.1055/s-0028-1086871

Choi JH, Stapf C, Marshall RS, Pile-Spellman J, Mohr JP, Mast H. Focal Neurological Deficits in Patients with Unruptured Brain Arteriovenous Malformation. Journal of the Neurological Sciences2009; 287: 126-130.

Choi JH, Watzke S, Preuss UW. Diagnostic correlates of Alzheimer Dementia in a US Nationwide Inpatient Sample. American Journal of Geriatric Psychiatry 2010; 18: 821-9.

Choi JH, Marshall RS, Neimark MA, Konstas AA, Lin E, Rundek T, Mohr JP, Mast H, Pile-Spellman J. Selective Brain Cooling with Endovascular Intra-Carotid Infusion of Cold Saline. AJNR Am J Neuroradiol 2010; 31: 935-939.

Giannopoulos S, Boden-Albala B, Choi JH, Carrera E, Doyle M, Perez T, Marshall RS. Metabolic Syndrome and Cerebral Vasomotor Reactivity. European Journal of Neurology 2010; 17: 1457-62.

Choi JH, Pile-Spellman J, Brisman J. Trends in the management of intracranial vascular malformations in the US. Stroke Research & Treatment [Open Access] 2012; 734871.

Choi JH, Pile-Spellman J, Brisman JL. US nationwide trends in carotid revascularization: hospital outcome and predictors of outcome from 1998 to 2007. ActaNeurolScand 2014; 129: 85-93.

Choi JH, Pile-Spellman J, Brisman JL. US nationwide trends in carotid revascularization: Is there a clinical opportunity cost associated with the introduction of novel medical devices? ActaNeurolScand 2014 ;129: 94-101.

Mangla S, Choi JH, Barone F, Novotney C, Libien C, Lin E, Pile-Spellman J. Endovascular external carotid artery occlusion for brain selective targeting: a cerebrovascular swine model. BMC Res Notes 2015; 8: 808.

Choi JH, Pile-Spellman J. Reperfusion changes after stroke and practical approaches for neuroprotection. Neuroimaging Clinics 2018; 28: 663-82.

Book Chapters:

Arteriovenous malformations and other vascular anomalies. In: Mohr JP, Wolf PA, Grotta JC, et al. (Ed). Stroke: Pathophysiology, diagnosis, and management. Elsevier Saunders, 5th Edition, 2011: 616-642.
Selective Brain Hypothermia. In: Romanovsky AA, (Ed). Thermoregulation, Part II. San Diego: Elsevier BV, 2018: 839-852.

Pathophysiology of arteriovenous anomaly-related hemorrhage. In: Lee SH, (Ed). Stroke Revisited: Hemorrhagic Stroke. Springer, 2018: 69-78.

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