NSPC Surgeon William Sonstein Co-Authors Article in Neurosurgery

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NSPC Surgeon William Sonstein Co-Authors Article in Neurosurgery 


Dr. William Sonstein

(January 29, 2024 – Rockville Centre, NY) William J. Sonstein M.D., F.A.C.S., a senior attending neurosurgeon and the President of NSPC Brain & Spine Surgery is one of the co-authors of an article to be published in Neurosurgery, the official publication of the Congress of Neurological Surgeons (CNS). Published monthly, this international medical journal features scientific articles on clinical or experimental surgery topics of interest to practicing neurosurgeons and other providers who specialize in the treatment of brain, spine, peripheral nerve conditions.

Entitled, “Development and clinical validation of a hook effect-based lateral flow immunoassay sensor for cerebrospinal fluid leak detection,” Dr. Sonstein’s article expands upon an oral presentation he delivered about a new, point-of-care cerebrospinal fluid (CSF) testing strip at the 2023 scientific meeting of the Congress of Neurological Surgeons (CNS) and offers evidence of the test strip’s efficacy.

An expert in complex spinal surgery, Dr. Sonstein worked with an international team to invent a new inexpensive, rapid, point-of-care cerebrospinal fluid (CSF) diagnostic testing strip.

It’s not uncommon for patients to exhibit a build-up of unknown fluids postoperatively, particularly after being treated for a lumbar spine condition. Since undiagnosed CSF leakage can lead to serious complications, including meningitis, abscess, and pneumocephalus, it is crucial to rule out the presence of a leak rapidly and noninvasively.

According to Dr. Sonstein, “a laboratory-based CSF test requires that a sample be sent out for analysis which can take days before results are returned. I knew there was a need for fast, in-hospital test that could be used as part of a daily, post-operative protocol to make sure patients were safe.” The test strip Dr. Sonstein helped to invent addresses this need by quickly indicating the presence of CSF without requiring outside testing or special training for the user. He hopes that other neurosurgeons, as well as orthopedic spine surgeons and emergency room surgeons will see the benefit in using this new diagnostic tool.


To learn more about Dr. Sonstein, please visit:



Photo caption: William J. Sonstein M.D., F.A.C.S., attending neurosurgeon and President, NSPC Brain & Spine Surgery.


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Founded in Freeport in 1958, NSPC Brain & Spine Surgery (NSPC) has grown to become one of the largest, private neurosurgical groups in the U.S. with seven conveniently located offices on Long Island and in Manhattan. The practice’s 15 experienced neurosurgeons are experts in “Bloodless” spine and brain surgery, including endoscopic spine surgery, radiosurgery, endoscopic brain surgery, and other minimally invasive techniques. These advanced procedures are used to treat herniated disc, spinal stenosis, brain tumors, brain aneurysms, trigeminal neuralgia, and other conditions. Please visit www.nspc.com for more information.